Botox Side Effects – What is Botox?

long term botox side effect

What is Botox?

Botox Side Effects – Botox is a brand name for a toxin produced by the Clostridium botulinum bacteria. There are other brands, such as Dysport and Xeomin.

Botox is commonly used by doctor to reduce a wrinkle and fine line.

Other than minimising wrinkles on the face, Botox injections can treat:

  • Excessive sweating (hyperhidrosis)
  • Jaw Botox – Jaw Reduction
  • Calf Reduction
  • Bladder overactivity

Continue reading to discover more about Botox’s safety, popular applications, Botox side effects, and more.

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botox side effects

What is Botox made from?

what is botox

Botox is a botulinum toxin type A-based injectable medication. The bacteria Clostridium botulinum produces this toxin.

The toxin that causes botulism (a life-threatening form of food poisoning) has different effects depending on the exposure. Botox, for example, is only administered in small, precise amounts.

Botox stops messages from your nerves to your muscles when injected. This stops the targeted muscles from contracting, which can help with muscle pain and wrinkles.



Is Botox a Safe Treatment?

Although botulinum toxin can be fatal in large concentrations, lower dosages, such as those used in Botox injections, are deemed safe and have a long safety track record.

Between 1989 and 2003, only 36 reports of adverse effects connected with cosmetic usage were reported to the US Food and Drug Administration (FDA). Thirteen of these instances may have been caused by an underlying ailment rather than the medicine.

Due to the low cases and track record , many medical experts is now administering Botox injections in their clinic for cosmetic reasons.

Although Botox is generally safe procedure, Botox injections should always be administered by a board-certified dermatologist or aesthetic doctor.

If your injections are not prepared and administered by doctor, you’re more likely to encounter negative side effects.

For pregnant or nursing mothers, you should postpone Botox treatment.

How is Botox Injection used?

Botox is most commonly used to minimize the appearance of wrinkles and fine lines. Most cosmetic concerns such as frown lines, crows feet, chin and neck wrinkles are treatable.

Other than wrinkles and fine lines, Botox injection is also effective to relax and shrink the muscles.

Botox calf reduction and Jaw Botox are gaining popularity for a smaller calf and jaw reduction slimming.

Botox can also treat the following conditions:

  • lazy eye
  • eye twitching
  • chronic migraines
  • neck spasms
  • overactive bladder
  • excessive sweating (hyperhidrosis)


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What are the Botox Side Effects?

botox side effects

Botox is permitted in Singapore for both medicinal and aesthetic purposes. The majority of the negative effects are attributable to the fact that it is a neuromodulator that relaxes the muscle by inhibiting nerve impulses.

Most patients will only experience mild Botox side effects, which are temporary with quick recovery period.

Potential Fever And Chills

Fever and chills are the most typically reported Botox adverse effects, however this varies depending on the kind of Botox administered. The flu-like symptoms disappear after two weeks.


Potential Headache

After Botox treatment on the forehead for fine wrinkles, a minor headache is common. It only lasts a few hours and will subside after some rest.


Redness / Irritation

Botox frequently causes redness at the injection site. It’s characterized by minor skin elevation and redness, which can be relieved by icing. People with sensitive, allergy-prone skin are more likely to experience inflammation.



The severity of the pain is determined by the region being treated as well as the amount of units administered. Although local anaesthetic is used to reduce discomfort, moderate pain is unavoidable because the process includes needles.


Potential Infection

When a needle is inserted, it leaves a tiny wound that can get infected by bacteria found in the skin’s regular flora. However, infection can be avoided by keeping good cleanliness before and after treatment. It’s preferable to keep the wound clean until it’s healed.



Swelling is an expected side effect of Botox injections because it is the body’s natural immunological reaction to an injury. It happens as a result of bleeding from blood vessels in the skin that have been injured by the needle, although it subsides within a few hours.


Eye Discomfort

Because of the eyes’ sensitivity to toxin, the physician must exercise extreme caution while injecting Botox into the area around the eyes. Excessive Botox can cause temporary dryness of the eyes, brow drooping, impaired vision, and a glaring glare. All of these adverse effects must be reported to your doctor, even if they subside after 3–4 months.


In very rare cases, some patients may experience botulism-like symptoms. Do seek for medical attention right away if you experience the following side effects after Botox injection:

  • difficulty speaking
  • difficulty swallowing
  • difficulty breathing
  • vision problems
  • loss of bladder control
  • general weakness

Botox Price Singapore

The price of Botox in Singapore usually range from $198 to $1800. The costs of Botox is based on:

1.  Brand of Botox (Botox, Dysport, Xeomin)

2. Target area (how many units are required?)


Forehead lines – Female  (Frontalis) $280 $250 8 – 25 units
Forehead lines – Male (Frontalis) $330 $300 8 – 25 units
Frown Lines – Female (Glabella) $280 $250 8 – 20 units
Frown Lines – Male (Glabella) $330 $300 8 – 20 units
Brow Lift

$198 per side

$160 per side 8 – 20 units
Crow’s Feet $198 per side $160 per side 8 – 20 units
Nose Lines (Bunny Lines) $280 $250 4 – 10 units
Nose Lines (Bunny Lines) $280 $250 4 – 10 units
Jaw Line – Female (Masseter muscles) $690 $598 40 – 80 units
Jaw Line – Male (Masseter muscles) $890 $790 40 – 80 units
Chin $230 $198 4 – 8 units
Gummy Smile $230 $198 4 – 8 units
Neck lines $790 $600 8 – 20 units
Dermalift Mirco-injections $790 $600 8 – 20 units
Sweat Control: Underarms / Palms $1500 $1200 100 – 120 units
Calf Reduction $1500 $1200 100 – 200 units
Ala Carte Add on Per Unit $15/ unit $12 / unit $12 / unit

*Price quoted all subject to prevailing government taxes. Prices is not fixed and depends on the unit required to treat.
*Units required is an estimation based on average patients. It is best to consult our doctor based on individual needs.


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What are the Long Term Botox Side Effects?

As the effects of Botox injections last between 4 – 12 months (depending on targeted area), most patients who rely on Botox will require many injections over time.

However, there is insufficient data to accurately determine the effectiveness and negative long term Botox side effects.

Based on a 2015 research, participants are required to have Botox injections every six months to address bladder issues. It was found that the danger of negative consequences did not grow with time.

People who had many injections showed higher long-term treatment benefit outcomes. However, according to the findings of a 2015 study, there are potential harmful effects that may develop after the tenth or eleventh injection.

These Botox side effects includes:

  • drooping eyelids
  • neck weakness
  • trouble swallowing
  • general weakness nausea vomiting
  • impaired eyesight
  • trouble chewing
  • heart palpitations difficulties speaking

To fully comprehend the possible long-term consequences, there need to be more long term studies.

long term botox side effects

Is Allergic Reaction Possible with Botox Side Effects?

Botox, like all other medications, can induce allergic reactions in certain patients. However an allergic reaction needs prior exposure to the toxin. It might range from moderate itching and redness to a full-blown anaphylactic reaction that can result in death.

To avoid such situations, the patient’s medical history should be shared with the clinic. The patient in the first occurrence of Botox allergy documented recovered without consequences.

How to Prevent Botox Side Effects?

To avoid the above-mentioned Botox side effects and guarantee the patient’s safety, it is very important that the Botox injection is performed by a certified and skilled aesthetic doctor.

The brand of the Botox should be FDA authorized and verified authenticity from authorised supplier.

Furthermore, the doctor should disclose and disclose the intended location to avoid mistakenly injecting Botox in another area.

Finally, the medical doctor should determine the dose to be given with precision.


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